Published by Peptide Protocols · Reviewed September 2026 · How we make these pages · Educational & research purposes only — not medical advice.
Among the growth-hormone-releasing peptides, tesamorelin stands out because it has an actual approved medical use and a very specific research reputation: reducing visceral (deep belly) fat.
Tesamorelin is a GHRH analog — a stabilized version of growth-hormone-releasing hormone. Instead of adding growth hormone directly, it nudges the pituitary to release the body's own GH in a more natural, pulsing pattern. It is FDA-approved under the brand Egrifta for a specific condition (HIV-associated lipodystrophy, an abnormal fat distribution), which is why it's better characterized than many peptides in this space.
For the side-by-side, see sermorelin vs ipamorelin and our growth-hormone peptides overview.
Vial mg + bacteriostatic water mL + your target mcg → mL and U-100 syringe units, instantly. Free, no sign-up, 60+ research peptides preset — plus dedicated calculators and BAC-water charts for BPC-157, retatrutide, tirzepatide, semaglutide, tesamorelin and CJC-1295/ipamorelin.
Open the free peptide calculator →Research & educational use only — never medical advice.
We do not recommend or partner with any peptide supplier. Use the checklist instead: third-party COAs that match your batch and lot, stated purity, clear research-use labeling, real support and proper cold-chain shipping.
The supplier checklist →Educational content only. Confirm the legal status where you live before ordering anything.
It's FDA-approved (as Egrifta) for HIV-associated lipodystrophy. Its signature research reputation is reducing visceral (deep abdominal) fat, which is why it draws broader metabolic interest.
It works by prompting the body's own growth-hormone release rather than adding GH directly; muscle effects aren't its defining feature — visceral-fat reduction is. Treat non-approved uses as research, not established.
Both are GHRH-based, but tesamorelin is a stabilized analog with an approved use and the visceral-fat reputation, while sermorelin is an older, shorter-acting fragment used more generally.
Our guides lay out the growth-hormone-releasing peptides — what each does, the timing, and the reconstitution math — without the hype.
Browse the shop on Etsy →The one formula, a BAC-water chart, and the 10 most-researched beginner peptides — the math done for you. Print it for the fridge.
🎁 Send me the free cheat sheet →